Support for Equine Insulin Resistance - Life Data® Blog

Support for Equine Insulin Resistance

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Life Data® Insulin R Formula FAQ

The Life Data® Insulin R Formula is designed to help reduce the symptoms associated with insulin resistant horses such as occasional bouts of laminitis, obesity, regional adiposities, thin soles, lethargy, and low exercise tolerance. Life Data® Insulin R Formula supplies active ingredients to assist with glucose metabolism, fat metabolism, insulin action and help reduce inflammation. The formula supports proper metabolism to encourage enhanced weight control and general health.

Research Behind Life Data® Insulin R Formula

Life Data® Insulin R Formula was formulated based on research, including whole blood macro and trace mineral analysis. Test results from horses diagnosed with insulin resistance were compared to healthy horses. The research was performed in our in-house laboratory equipped with conventional equine hematology and chemistry equipment (Abaxis HM5 and VetScan VS 2) and specialized equipment such as CEM Mars 6 microwave digestion and Thermo iCAP RQ ICP-MS.

Insulin Resistance Testing and Field Trials

Diagnostic testing, insulin testing, and other additional tests were performed by the horse owner’s veterinarian. Life Data conducted two years of field-trial testing on insulin resistant horses, with intermittent retesting on these horses. A survey of the 20 horses completing the field-testing trials showed that 50% of horse owners reported the product had “Pronounced Improvement” of “General well-being”, 35% showed some improvement and 15% reported no improvement.

Support for Equine Insulin Resistance

In addition to the benefits of Life Data® Insulin R Formula, Farrier’s Formula® or Farrier’s Formula® Double Strength given along with Life Data® Insulin R Formula helps build the connective tissue of the hoof wall, creates a denser hoof wall, and increases the growth rate to give the farrier more to work with.

Life Data® Insulin R Formula is not a treatment for insulin resistance, has not been proven to significantly reduce blood insulin levels, and is not intended to replace any veterinary prescribed therapeutics. A minimum of 6 to 8 months of administration is required before owners typically notice any changes in their horse. Additional information about the Life Data® Equine Nutrition Research program, the blood testing laboratory, and the Life Data® Insulin R Formula can be found on our website www.lifedatalabs.com .

Our goal is to help horses. By determining how nutrition impacts horses with specific conditions we hope that specific dietary changes can prevent these conditions or improve the lives of afflicted horses.

Ingredients that Benefit Horses with Insulin Resistance

Life Data® Insulin R Formula Active Ingredients:

  • Inositol
    • Also known as vitamin B8, has been shown in laboratory studies to increase insulin sensitivity and insulin signaling
      • (The Journal of Nutritional Biochemistry, Volume 24, Issue 2, February 2013, Pages 457-466; Int J Endocrinol, 2018; 2018: 1968450.)
  • Choline
    • Works synergistically with inositol as components of the phospholipids in cell membranes. Choline and phosphatidylcholine intake have been associated with a lower Type 2 diabetes risk in Finnish men.
      • (European Journal of Nutrition volume 59, pages 3857–3861 (2020))
  • Thiamine
    • Or vitamin B1, is essential for glucose metabolism
      • (Acta Diabetol. 2008 Sep;45(3):131-41. doi: 10.1007/s00592-008-0042-y.)
  • Chromium
    • Is necessary for proper insulin function and to help maintain appropriate blood glucose levels. Chromium helps maintain insulin receptor function on cells.
      • Human research: (Diabetes Educ. 2004;Suppl:2-14.)
  • Vitamin E
    • (Supplied as natural source vitamin E) Is an antioxidant that helps reduce inflammation and resulting tissue damage. Oxidative stress from a lack of antioxidants may contribute to insulin resistance. Sufficient vitamin E is usually present in green pasture grass; however, is deficient in stored hay. Vitamin E has been shown to improve insulin sensitivity in overweight human patients.
      • (Diabetes Care 2004; 27(9):2166–2171)
  • Tyrosine
    • An amino acid, helps regulate thyroid and adrenal hormones. Tyrosine is a building block of thyroid hormones and is therefore involved with metabolism.
  • Threonine
    • An essential amino acid, is necessary for collagen formation.
  • Vitamin D3
    • Functions as a hormone as it circulates through the blood stream. Fresh pasture grass contains vitamin D2; however, vitamin D levels drop quickly in stored hay. Horses stalled due to metabolic issues with pasture restriction may not receive enough sunlight for the skin to produce sufficient vitamin D. [Vitamin D reduces insulin resistance probably through its effect on calcium and phosphorus metabolism and through up regulation of the insulin receptor gene.
      • (Diabetology & Metabolic Syndrome volume 5, Article number: 8 (2013))]
  • Copper Amino Acid Complex
    • Low copper levels have been associated with insulin resistance and higher iron levels.
  • Proprietary Silicon Complex
    • Contains macro and trace minerals that are typically in low levels in the whole blood of horses with insulin resistance, as determined by research conducted in the Life Data® blood testing laboratory.
Product Char for Specific Conditions